Kvinslend universiteti: kasalxona dorixonasida aniq 3D bosma dori vositalari haqiqatga aylanadi

3D printing techniques are used for drug manufacturing, and due to accurate control of the pore structure, it can be used according to the patient's actual needs of personalization, there is a huge potential, and there are many companies in this field. Research and testing.

3D bosib chiqarish tabletkalari tezda eritilishi mumkin, Aprecia'dan olingan rasm

202-yil 13-fevralda Kvinslend universiteti (UG) tadqiqotchilari bemorlarga shaxsiy tibbiy yordam ko‘rsatuvchi kelajakda 3D bosib chiqarishni o‘rganishdi va tegishli maqolalarni chop etishdi.

Farmatsevtlarning fikriga ko'ra, Kvinslend universiteti doktoranti, maqolalarning asosiy muallifi, qog'ozning asosiy muallifi, 3D bosib chiqarish texnologiyasi keyingi bir necha yil ichida shifoxona va dorixonalarda maxsus dozalarni amalga oshirish uchun etarli. Ushbu tadqiqot orqali tadqiqotchilar Avstraliyada ham 3D bosma dori vositalarini ishlab chiqishni tezlashtirishga umid qilishdi.

Kruger said: "3D printing technology is often used in other medical applications, such as dental, orthopedic implants, however, in the pharmaceutical field, the use of 3D printing technology is lagging behind. Through this study, we want to drive 3D printing The development of pharmaceutical technology, this is a chance to the future of the Australian pharmaceutical industry. "

Spritam is the world's first 3D printing drug approved by FDA, sold by Aprecia Pharmaceutical. For treatment of seizures, 3D print pills have high porosity than traditional manufacturing pills, which means they are soluble and act faster in the body. Picture of Aprecia

3D bosib chiqarish farmatsevtika taraqqiyoti

Materiallarni qo‘shish klinik farmatsevtika rivojlanishi uchun ko‘plab afzalliklarni berdi, masalan, bemorning ehtiyojlariga moslashtirilgan davolanish, dori yetkazib berish vaqtini tezlashtirish va talabga- erishish, ammo laboratoriyadan boshlab 3D bosib chiqarish dori texnologiyasi klinik o'tishlar Boshlanish bosqichi.

Farmatsevtika sanoatida 3D bosib chiqarish, Fabrx dan rasm

Biroq, bu soha o'ziga xos rivojlanishga ega, ayniqsa Aprecia, 2015 yilning boshida 3D-bosma dori vositalarining birinchi roziligini olgan. Aprecia tomonidan ishlab chiqilgan Spritam preparatlari epilepsiyani davolash uchun tasdiqlangan, shundan so'ng ular RD bilan hamkorlik qilish orqali ishlab chiqarish ko'lamini kengaytirishda davom etmoqdalar. BATTELLE kompaniyasi.

Aprecia moslashuvchan dori ishlab chiqarish platformasi orqali bolalarning noyob metabolik kasalliklarini davolash uchun moslashtirilgan dori ishlab chiqdi va ko'rish to'siqlari bo'lgan bemorlarga yordam berish uchun Brayl va oy naqshlari bilan 3D bosib chiqarish tabletkalarini yaratdi.

Bundan tashqari, global farmatsevtika kompaniyasi Merck va EOS AMCM qo'shma loyihani ishga tushirdi, 2020 yilda 3D bosib chiqarish tabletkalarini ishlab chiqdi va ishlab chiqardi, avval klinik sinovlar uchun, keyin esa tijorat ishlab chiqarish.

Xitoyda, shuningdek, 3D bosma dori-darmonlarni tadqiq qilish bo'yicha juda kam kompaniyalar mavjud, eng ko'p vakili 2015 yilda Nanjing Sanshi Jialsni tashkil etishdir. Ular yangi 3D bosib chiqarish dori texnologiyasi platformasini qurish, farmatsevtika dozalash shaklini shakllantirish, Raqamli rivojlanish, to'liq zanjirli xususiy texnologiyani aqlli ishlab chiqarish. Ayni paytda, AQSh FDA rivojlanayotgan texnologiya loyihasi uchun tanlangan birinchi Xitoy farmatsevtika korxonasi sifatida San-Tval Amerika Farmakopeyasi 3D bosma dori sanoati standartlarini ishlab chiqishda ishtirok etmoqda.

3D chop etish tabletkalari tibbiyotning kelajagimi?

Kvinslend universiteti farmatsevtika mahsulotlarini 3D bosib chiqarish sohasida so'nggi tadqiqotlarni o'tkazdi. Tadqiqot shuni ko'rsatadiki, bu texnologiya hozirda etarlicha mukammal va kelajakda shifoxonalar va dorixonalarda qo'llaniladi.

Kruger said: "3D printing technology can be tailored to the patient to ensure that it has an accurate dose or combination that meets specific needs. With 3D printing, we can combine five pills into one, and even change the size of the pill. , Shape, color, taste, or texture. "

3D bosib chiqarish dori vositalari muhim afzalliklarga ega bo'lsa-da, ular tibbiy muhitda keng qo'llanilishi kerak, ammo ba'zi muammolarni hal qilish kerak.

Qiyinchiliklardan biri bu chop etish vaqti. Muntazam nuqtai nazardan, taxminan 3 daqiqa davomida chop etish uchun taxminan 3 daqiqa vaqt ketadi va 28 tabletkadan iborat partiya taxminan 45 daqiqa davom etadi. Klinikani dori-darmonlarni joylashtirishni kutish uchun bu juda uzoq va siz haqiqiy dunyoda amalda qo'llash uchun vaqtni qisqartirishingiz kerak.

Biroq, maqolaning umumiy muallifi, Kvinslend universiteti dotsenti Amirali Popatning fikricha, 3D bosib chiqarish bemorga dori-darmonlar turini kamaytirishi mumkin.

He said: "Multi-drug treatment refers to the use of five or more drugs at the same time, about two-thirds of 75-year-old Australians are in this treatment. The true benefits of 3D printing pills are consumers or patients, though There is also a road to go before the implementation, but this is a very exciting development trend. "

Tadqiqotchilarning ta'kidlashicha, ushbu tadqiqot Kvinslend universitetining real dunyoda shaxsiylashtirilgan tibbiy fizibilite bo'yicha boshlanishi, hozirgacha to'plangan ma'lumotlar umid qilinmoqda.

The National Chairman of the Chrisfreeman, the National Chairman of the Chrisfreeman, the Australian Pharmaceutical Association said: "3D printing in the future can help people who need a variety of drugs in the correct time, the correct dose takes the right drug."

For more information on this study, see the title "3D Printing: Potential Clinical Applications for Personalised Solid DoseMedics", published in the Australian Medical Journal. The common author of the study was L. Krueger, J. Miles, K. Steadman, T. Kumeria, C. Freeman and A. Popat.